Cheap analogs Nize gel and tablets


Nise is an excellent analgesic and antipyretic agent. This analgesic is prescribed during various diseases. He is popular for his ability to act quickly and delay pain for a long time.

It happens that this medical product is not in pharmacies or it is more profitable for a person to buy its equivalent (generic), then it is natural that he wants to know what this product can be replaced with.

A little about nyz tablets

Nise has a wide range of activities and for this he is grateful to his active element, which is in its composition - this is nimesulide.

Each tablet contains it in 50 mg or 100 mg.

There are 10 of them in the blister.

Nise is a non-steroid drug that comes in the form of:

It is used to treat a variety of diseases of the joints, bones, tendons. Nise tablets have a pronounced pain-free effect.

Since this drug product has an analgesic effect, it is often recommended for diseases of the joints:

  • Arthritis
  • Radiculitis
  • Gout inflammation,

In addition, doctors prescribe nize with problems in tendons and in the area of ​​interarticular cartilaginous tissues.

  • Bruises
  • Tendon recovery after injury
  • During the rupture of the ligaments,

An indispensable assistant, Nize has proven himself to:

  • Headaches,
  • Toothache,
  • During periods of painful menstruation.

And this is a small list where you can use the Nise.

Contraindications to the use of tablets:

  • In the period of acute gastrointestinal diseases,
  • Ulcers and bleeding of the digestive system,
  • Liver failure,
  • "Aspirin triad",
  • Obvious disease of kidney failure
  • During pregnancy,
  • And during lactation,
  • It is forbidden to children up to 12 years old tablets Nise,
  • Allergic reaction to one of the components of the goods.

Cheap Nise analogues

Everyone who buys this medicine in a pharmacy wants to know which Naiza counterparts are in the “cheaper” category. There is a list of drug products, which in their own action and properties are similar to the tablets of Nise, and the price category is somewhat lower.

The list of analogues tablets Nise includes a lot of medications.

But, attention, this product is just an analog of Knight.

Before you replace the original with a generic, consult your doctor.

A list of similar drugs:

      • Alit. Such a drug can relieve pain of a different etiology: headache, toothache, muscle and joint pain, periodic female pain. Discharged with pharyngitis, tonsillitis, otitis. The inflammatory process in the musculoskeletal system. Pain after surgery. Infectious-inflammatory process, accompanied by fever. A variety of colic: kidney, liver, intestinal and the like. Contraindications: gastric and duodenal ulcers, liver and kidney problems, glaucoma, obstructive diseases of the gastrointestinal tract, biliary and urinary tract, paralytic ileus of the intestine, severe pseudo-paralytic myasthenia, hypersensitivity to the components of the drug, pregnancy, pregnancy, pregnancy, severe pseudo-paralytic myasthenia, hypersensitivity to the components of the drug, pregnancy, pregnancy, adherence, pregnancy, adherence, pregnancy; years old.
      • Amelin. It is used during acute pain, used by women with primary dysmenorrhea. Osteoarthritis with severe pain is treated.
      • Aponil. Acute pain, primary dysmenorrhea, pain in osteoarthritis. Contraindications: aspirin asthma, bleeding in the gastrointestinal tract, during periods of exacerbation of ulcers, severe malfunctions of the liver and kidneys, 3 trimester of pregnancy, children under 12 years old, prohibited during breastfeeding, allergic reactions to aponil.
      • Nysik. It is indicated for diseases: osteoarthritis, osteoarthrosis, inflammation in injuries (dislocation, contusion, stretching and the like). It is used by dentists, gynecologists, ENTs. Soothing feverish state. Used during recovery after surgery. Contraindications: allergies to the drug, pregnancy and lactation, liver failure, a severe form of blood clotting and kidney disease, periods of exacerbation of diseases in the gastrointestinal tract.
      • Nigan. It is similar in use to Aponela and Amelin.
      • Nmegezik.
      • Nimesil. Treatment of acute pain, dysmenorrhea, is used as a means of the second action. Contraindications: allergy to the drug, alcoholism and drug addiction. Severe forms of blood clotting, heart failure, kidney and liver function. During periods of increased body temperature. 3 trimester and lactation. Children under 12 years old. Ulcer, the active form of the disease in the digestive tract.
      • Nemisin.
      • Nimesulide. One of the cheapest analogues tablets Nise. This drug is recommended by dentists to their patients, gynecologists. He is able to relieve pain in the period of headache, during rheumatoid arthritis, osteochondrosis. Can be used in post-traumatic periods.

        Contraindications: ulcer, exacerbation of the disease in the gastrointestinal tract, kidney and liver failure.
        Severe conditions: heart failure, problems with blood clotting. Allergic reactions to the components in the composition of Nimesulide.
        Pregnancy 3 trimester, breastfeeding period.
        Children up to 12 years.
        Also, do not use when alcoholism, drug addiction, with fever.

      • Nimid. Used to treat pain in bones, joints, muscles. He proved himself as a good analgesic after surgical interventions. Relieves toothache, pain during menstruation, is used in ENT practice. Contraindicated in patients with a tendency to bleeding, with suspected surgical pathology, gastrointestinal problems, ulcers, fevers and the like.
      • Nimujet. Treats pain syndrome of various origins. Contraindications: peptic ulcer in active form, moderate or severe hepatic and renal failure, hypersensitivity to the drug.
      • Nimulid.
      • Nimika. It is manufactured as dispersible tablets. One pack contains 20 pieces. Produces India. It has antipyretic, anti-inflammatory properties.
      • Pansulid.
      • Sisnaid. Treats rheumatic pains in joints and pains outside joints in soft tissues. Pain caused by inflammation in the body. Used after injuries and in the postoperative period. Practiced in the gynecological, dental field. Removes heat. Contraindications: peptic ulcer of the stomach or duodenum, severe impaired liver and kidney function, individual sensitivity to the components of the drug, pregnancy 3 trimester, lactation. Children under 3 years.
      • Sulidin. It is indicated for periarthritis, osteoarthritis, tendinitis, lumbago, during sprain stretching, inflammatory processes in the locomotor system. Contraindications: hypersensitivity to the components of the drug, dermatitis and infectious skin diseases, pregnancy, lactation. Children's age up to 12 years.

Among other drugs that are generic, there are the following:

      • Auronim. Produces India. It relieves inflammation in the postoperative period, removes fever, soothes pain during acute inflammation in the upper respiratory tract, used by women with dysmenorrhea disease. It also treats diseases associated with arthritis.
      • Aktosulid. This medicine is produced in Serbia and Montenegro. Indications for use: headache and toothache, dysmenorrhea, various arthritis, tenditis, bursitis, myalgia and the like.
      • Mesulide. Supplier Ireland. Primary dysmenorrhea, acute pain due to inflammatory processes in the body, symptomatic treatment of osteoarthritis with pain.
      • Coxtral. Produces Czech Republic. Arthritis of different etiology, pain after surgery and after injuries, algomenorrhea, feverish conditions, toothaches and headaches.

What is the difference from the original analogs

When a drug is first developed, a pharmacological company buys a patent for it. That is, the brand and product names. A patent is the right of the owner and no one will be able to produce such products except this company.

A patent is established for a specific time by law. In this way, pharmacological production pays for the costs of research and testing that were carried out with the drug.

Analogue is a repetition of a medical product that is no longer protected by a patent. Its components partially or completely copy the original, they have the same effective effect, but are not protected by a security document.

The pricing policy of the generic is significantly lower, since their release does not require additional research or testing. After all, all chemical formulas are borrowed from the original drugs.

Analogs, unlike the original Nise medication, have different colors, shapes, and flavors.

But the most important difference is the side effects. They should be carefully studied so that in situations where they manifest, cancel them.

Among the advantages of analogues are the following:

      • Lower price
      • Such drugs are well studied for efficacy and safety before they are released,
      • A variety of similar tablets give the choice of what to take,
      • Use generic can people with different income levels.

Among the minuses note the following:

      • Manufacturers of such drugs do not reveal until the end of the entire mystery of production. Therefore, during the manufacture of analogues, they may not adhere to the full technology and do not report all the components of the product,
      • Some made analogs of Nise have a low level of quality,
      • Nise's original tablets are produced in laboratories on high-tech equipment and with a high degree of material purification. Small pharmaceutical production may not have such capabilities, therefore they use old equipment and inexpensive auxiliary elements.
      • In our country, they do not practice qualification for generics, as they do abroad, so it is difficult for our customers to appreciate the effectiveness of one or another analogue.

How to choose a generic?

Of course, many people prefer to buy cheaper analogues of drugs, because the originals for some versts of the population are simply unavailable in price.

But before you buy an analog Nise, tell your doctor. Perhaps the medicine will not work for you or there are serious contraindications.

And a few tips on how to choose the right generic:

      • First: never replace the original medicine by yourself with an analog. This must be done by your health care provider. It is he who knows what will suit you as a replacement.
      • It is worth acquiring generics only in large pharmacy chains. First, there are good specialists working there, and they will be able to advise you on this issue. Secondly, in such places there is less risk to buy a fake.
      • After purchasing the drug, carefully read the instructions. Abstract should be on quality paper, with a clear font. It should include the address, telephone number of the pharmacological company that manufactured the analog.
      • The cheapest means can cost so, because they are made of low-quality material or on old equipment. Therefore, do not give them preference.

Let's summarize the final line: There are many analogues, but you shouldn’t replace the original with a generic one yourself, it’s better to go to a doctor for help. He will explain to you the feasibility of such a replacement, sometimes, it happens that the disease requires the original, because it acts much faster from the analog.

All other cases: A generic has long won the hearts of people for their ability to help and low cost.

About the drug

Drug medication that has analgesic and anti-inflammatory effect in many pathological processes.

The effect of the use of drugs based on the reaction of the body to its composition. The active substance is nimesulide.

Available in the form of conventional and dispersible tablets, also in the form of medicinal powder for the preparation of suspension and gel for external use.

Regardless of the form of release, the indication for the appointment are pain and inflammation in diseases:

  • arthritis of the psoriatic or rheumatoid type
  • sciatica or sciatica
  • joint disorders in rheumatism or gout,
  • spondylitis or osteochondrosis,
  • lumbago or arthritis,
  • myalgia or arthralgia,
  • feverish state
  • inflammation of the soft tissue after injuries,
  • bursitis or tendon damage,

Nise tablets and suspension are used to eliminate pain, dental, menstrual and headache. Nise gel is recommended for traumatic injuries and after operations performed on muscles, bones or joints.

Instructions for use of the drug warns about the undesirable use of the drug in tablets and in the form of suspensions in pathologies:

  • erosion or ulcers on the mucous membranes of the gastrointestinal tract,
  • liver / kidney dysfunction,
  • aspirin triad.

The drug is not recommended in the age of a child under two years.

Gel Nise is not prescribed for the defeat of the skin by infection or dermatosis.

Absolute contraindications for any form of analogue production are considered the period of pregnancy / lactation and sensitivity to the existing composition.

Side effects of the drug is not small, but they occur most often in overdose or the presence of contraindications. When an adverse reaction occurs in a patient, the symptoms are:

  • violations of the stomach and intestines,
  • migraine,
  • allergy (including anaphylactic shock),
  • circulatory disorders.

The average price for Nise gel and tablets is 200 rubles, suspension powder is 300 rubles.

Similar medicines

If necessary (due to high prices, contraindications, side effects, etc.), you can replace Nise with analogues. Depending on the evidence, as well as the reasons for finding a substitute, the doctor may prescribe analogues cheaper than the original or more expensive. It should be borne in mind that some analogues of this group are sold in pharmacy chains only by prescription.

Nimesulide and Ibuprofen are substitutes that are much cheaper than the original.

Direct analogue of Nise gel and tablets. The drug is used to treat inflammatory diseases of the musculoskeletal system and other body systems. Also, tablets and gel for external use are used as a strong painkiller for various forms of pain.

The active substance has a name identical to the name of the drug - Nimesulide. Tablets contain 100 mg. the main component and additional substances necessary to enhance the action of the composition.

List of direct indications:

  • osteoarthritis,
  • dysmenorrhea,
  • migraine,
  • toothache,
  • muscle injuries of the joints or bones,
  • pathology of the musculoskeletal system.

The analogue of the Nise tablets is contraindicated in case of damage to the gastrointestinal tract mucous membrane, heart failure, and the gel-like substitute is recommended for open wounds and skin infections.

  • children's age (up to 12 years),
  • intolerance to the components of the composition,
  • blood pathology,
  • kidney / liver disease,
  • alcohol addiction,
  • allergic to one or more substances from the composition of the drug.

Cheap analogue Nise can provoke side symptoms:

  • pain in the epigastric region, nausea, severe heartburn, change of stool,
  • constant dizziness or drowsiness,
  • erythema, rash, or urticaria,
  • slowing the output of fluid from the body, swelling,
  • thrombocytopenic purpura.

The price of the drug Nimesulide - from 80 rubles.

Another cheap analogue of Nise gel and other forms of release is Ibuprofen. The drug has a wide range of effects and is recommended to provide analgesic, antipyretic, as well as anti-inflammatory effect.

  • tabletted (prolonged, usual and for resorption),
  • prolonged capsules
  • suspension,
  • gel and cream

The active component of the analogue is ibuprofen.

Instructions for use include the following indications:

  • signs of viral disease (ARVI / flu),
  • arthritis (psoriatic), osteoarthritis and spondylosis,
  • migraine, myalgia and neuralgia,
  • spinal artery syndrome, Barre-Lieu or nephrotic,
  • bursitis, tendonitis and hematomas,
  • hypotension, ankylosing spondylitis, fever,
  • injury to soft tissue or bone.

An inexpensive analogue is also used for the treatment of sprains, arthritis (rheumatoid), articular syndrome, or radiculitis.

The list of contraindications to the use of drugs - an extensive. The main contraindications of Ibuprofen include:

  • the presence of ulcers or erosion on the walls of the stomach or intestines (with the exception of the use of the gel),
  • sensitivity to the existing composition,
  • pathology of the optic nerve and abnormalities regarding the function of color visual perception,
  • aspirinovaya asthma,
  • hypertension, amblyopia or scotoma,
  • violation of the full functioning of the kidneys / liver,
  • heart failure,
  • hemophilia, edema, leukopenia,
  • third trimester pregnancy.

The Russian drug causes side effects affecting the nervous, digestive, circulatory and urinary systems. An allergic reaction is also possible.

The cost of drugs - from 70 rubles, depending on the form prescribed by a specialist.

Anti-inflammatory drug with analgesic effect of Nimesil, included in the list of drugs - Nise's analogues.

The drug is produced only in the form of a powder for dissolving and preparing a suspension. The active ingredient is nimesulide.

  • infectious inflammations
  • inflammatory and degenerative processes affecting the musculoskeletal system,
  • gynecological, urological and vascular inflammatory diseases,
  • post-traumatic complications,
  • dental diseases
  • migraine.

Positive feedback Nimesil deserved the elimination of pain during menstruation and as a febrifuge.

Before use, you should read the contents of the instructions, which include contraindications:

  • inflammatory processes in the digestive tract,
  • installation of a shunt in the aorta,
  • fever,
  • intolerance to any constituent substances.

A negative reaction of the body to the Nise analog is expressed in the following signs: cardiac arrhythmia, headaches, bowel disorder and allergies.

The price of Nimesil is from 500 rubles.

A good analgesic and pain reliever - Nimulid, developed on the basis of nimesulide, as an active substance. Among the drugs that replace Nise, Nimulid is considered one of the most effective; in addition, the drug has several forms of release. Lingual, ordinary tablets and suspension. Also, a drug in the form of an ointment can replace Knight gel.

The use of drugs is recommended when diagnosing a patient:

  • arthritis of rheumatoid or psoriatic nature,
  • bursitis, injuries of the musculoskeletal system,
  • osteochondrosis or spondylitis,
  • articular gouty syndrome
  • myalgia.

  • erosive - ulcerative damage to the mucous walls of the stomachs or intestines,
  • diseases that develop in the liver or kidneys,
  • susceptibility to allergies, including intolerance to the composition,
  • pregnancy / lactation.

Adverse symptoms are more often manifested by headaches and severe weakness. In the treatment of ointments possible local allergic reaction.

Analogue is cheaper than Nise - from 170 rubles.

The non-steroid drug Aertal is a substitute for the Nise in three main forms (tablets, gel and suspension). However, unlike Naiz, Aertal contains the main component, aceclofenac, eliminating pain and preventing the inflammation process.

Treatment is recommended for pathologies:

  • periarthritis in the shoulder and scapula,
  • lumbago,
  • rheumatism, progressive in soft tissues,
  • osteoarthritis,
  • dental pain
  • rheumatoid arthritis
  • ankylosing spondylitis.

The cream can be used to relieve tissue swelling and eliminate pain of a limited nature (for example, in case of injuries).

  • damage to the walls of the digestive tract,
  • hives,
  • bronchospasm
  • medicinal rhinitis,
  • liver dysfunction
  • circulatory pathology,
  • hyperkalemia,
  • woman bearing a fetus,
  • breastfeeding
  • childhood.

Before the start of treatment with the drug Aertal, attention should be paid to the signs of side effects associated with the disorder of the functionality of the stomach / intestine and nervous system. An allergic reaction is possible.

Price Aertal - from 270 rubles.


The drug Aceclofenac with analgesic, antipyretic and anti-inflammatory action belongs to the group of analogues of the drug Nise.

Release form one - tablets, which contain a medicinal substance - aceclofenac.

Indications for symptomatic therapy:

  • spondylitis
  • arthritis
  • periarthritis,
  • osteoarthritis,
  • inflammation of soft tissue (rheumatoid).

  • age of patients under 18 years old
  • gastrointestinal tract pathologies associated with the presence of ulcers or erosion,
  • aortic bypass
  • heart failure,
  • lactation / pregnancy
  • allergic to the drug composition of the drug.

Side effect is manifested by the digestive tract, circulatory and nervous systems, as well as in the form of allergies.

Cost analogue Nise - from 230 rubles.


Given all the features of treatment with drugs of this group, experts are of the opinion that the Nise analogues have more flaws than the original. However, it is impossible to determine what is better for the patient in each particular case. Sometimes cheaper counterparts are more effective than the original drug with a high cost. The impact of drugs on the body often does not depend on the price, so the choice of drugs should be trusted only to the attending physician.

For the treatment and prophylaxis of back and joint diseases, our readers use the fast and non-surgical treatment method, which is gaining popularity, recommended by leading orthopedic surgeons. After carefully reviewing it, we decided to offer it to your attention.

For the treatment and prophylaxis of back and joint diseases, our readers use the fast and non-surgical treatment method, which is gaining popularity, recommended by leading orthopedic surgeons. After carefully reviewing it, we decided to offer it to your attention.

Available analogues tablets nise

Analogue cheaper from 100 rubles.

Nimesulide is one of the cheapest analogues of Nise, of Macedonian origin. Also available in tablet form and contains in 1 tablet the same amount of active substance (nimesulide) - 100 mg. It is indicated for use in rheumatoid arthritis, osteochondrosis, dental and headache, as well as in post-traumatic inflammation of soft tissues. From contraindications can be noted renal insufficiency, children's age (up to 12 years), periods of pregnancy and lactation. A full list of contraindications and interactions with other drugs will be presented to you by your doctor.

Aponil (tablets) → synonym Rating: 405 Up

Analogue cheaper from 76 rubles.

Aponil is a little more expensive than Nimesulide. This analogue is also available in the same form. Sold in cartons of 20 coated tablets. Aponil has antipyretic, anti-inflammatory action. Nimesulide is used as an active ingredient in a dosage of 100 mg. on the pill. Contraindicated in disorders of the gastrointestinal tract, kidney and liver function, children under 12 years of age and aspirin asthma. During periods of pregnancy and lactation is prescribed in rare cases and only under the supervision of the attending physician.

Nimika (tablets) → synonym Rating: 278 Up

Analog more from 39 rubles.

Nimika is a slightly more expensive counterpart to Nise. Available in the form of dispersible tablets, in 1 package of 20 pieces. The active substance and its dosage in one tablet are similar to the substitutes indicated above. Indications and contraindications for Nimika also very similar and differ slightly. Regarding the interaction Nimik with other drugs should be found out from a specialist. Tablets can cause various side effects from the digestive system and the skin, so you should consult a doctor before taking.

How to find a cheap equivalent of expensive medicine?

To find an inexpensive analogue of a drug, a generic or a synonym, first of all we recommend to pay attention to the composition, namely to the same active ingredients and indications for use. The active ingredients of the drug are the same and will indicate that the drug is synonymous with a drug that is pharmaceutically equivalent or a pharmaceutical alternative. However, do not forget about the inactive components of similar drugs that may affect safety and efficacy. Do not forget about the advice of doctors, self-treatment can harm your health, so always consult with your doctor before using any medicine.

On the sites below you can find prices for Nise and find out about availability at a pharmacy nearby.

Nise instruction

to use the drug

Dosage Forms
Gel 1%

Anti-inflammatory drugs of different groups

International non-proprietary name

Vacation order

The active substance is nimesulide.

pharmachologic effect
Anti-inflammatory, antipyretic, analgesic. Selectively inhibits cyclooxygenase-2, inhibits the synthesis of prostaglandin in the focus of inflammation. It inhibits lipid peroxidation, does not affect hemostasis and phagocytosis. After ingestion is well absorbed from the gastrointestinal tract. The maximum concentration is reached in 1.5-2.5 hours. The half-life is 2-3 hours. Biotransforming in the liver. The main metabolite is pharmacologically active hydroxynimesulide. Excreted mainly by the kidneys. With prolonged use does not cumulate. Nise Gel is a nonsteroidal anti-inflammatory drug (NSAID) of the new generation from the sulfonamide class. It has a local anesthetic and anti-inflammatory effect. When applied topically, it causes weakening or disappearance of pain at the site of application of the gel, including pain in the joints at rest and during movement, and reduces morning stiffness and swelling of the joints. Promotes increased range of motion.

Indications for use
Osteoarthritis, osteoarthritis, bursitis, tendonitis, pain and inflammatory processes (with injuries, in the postoperative period, gynecological and infectious and inflammatory diseases). Nise gel: inflammatory and degenerative diseases of the musculoskeletal system (articular syndrome with rheumatism and exacerbation of gout, rheumatoid arthritis, psoriatic arthritis, ankylosing spondyloarthritis, osteoarthritis, osteochondrosis with radicular syndrome, radiculitis, inflammatory lesion, inflammatory lesion, inflammatory lesion, inflammatory lesion, radicular syndrome, radiculitis, inflammatory lesion . Muscle aches of rheumatic and non-rheumatic origin. Post-traumatic inflammation of the soft tissues and the musculoskeletal system (damage and tears of ligaments, bruises).

Hypersensitivity, gastric ulcer and duodenal ulcer in the acute stage, pronounced disorders of the liver and kidneys, bleeding from the gastrointestinal tract, type 2 diabetes, arterial hypertension, congestive heart failure, pregnancy, lactation. Restrictions on the use: children's age (up to 12 years).

Side effect
Headache, dizziness, drowsiness, very rarely - thrombocytopenia, nausea, heartburn, stomach pain, tarry stools, melena, petechiae, purpura, oliguria, allergic reactions (exanthema, erythema, urticaria). Nise gel: Local reactions: itching, urticaria, peeling, transient discoloration of the skin (not requiring the abolition of the drug). If any adverse reactions occur, discontinue use of the drug and consult a doctor. When applying the gel on large areas of the skin, the development of systemic side reactions is possible: heartburn, nausea, vomiting, diarrhea, gastralgia, ulceration of the gastrointestinal mucosa, increased liver transaminases, headache, dizziness, fluid retention, hematuria, allergic reactions (anaphylactic shock, skin rash), thrombocytopenia, leukopenia, anemia, agranulocytosis, lengthening of the bleeding time.

It can increase the effectiveness and toxicity of many drugs, due to their displacement from the sites of binding to plasma proteins and an increase in the free fraction in the blood (with simultaneous administration of hydantoin and sulfonamides, regular medical monitoring is necessary). Enhances the effect of drugs that reduce blood clotting, increases the level of lithium in the plasma.

Symptoms: increased severity of side effects. Treatment: gastric lavage, the appointment of activated carbon.

Dosing and Administration
Outwardly. Wash and dry the skin before applying the gel. Apply a gel column of about 3 cm in length to the area of ​​maximum pain without a uniform thin layer, without rubbing it 3-4 times a day. The amount of gel and the frequency of its use (no more than 4 times per day) can vary depending on the size of the treated area and the response of the patient. The maximum dosage is 5 mg / kg / day (30 g of gel per day). Do not use the gel for more than 10 days without consulting a doctor.

special instructions
With caution prescribed to elderly patients, with cardiovascular diseases, including hypertension, bleeding tendency, disorders of the upper GI tract, impaired renal function, during treatment with anticoagulants and antiplatelet agents. If a visual impairment occurs, you should immediately stop taking the drug and consult an optometrist. Patients with diabetes mellitus and patients on a low-calorie diet should take into account that sucrose is included in the preparation. With caution prescribed to patients whose work is associated with the need for increased attention and reaction rate.

Storage conditions
List B. At a temperature not higher than + 25 ° C in the reach of children.

Dr. Reddy `s Laboratories Ltd (India)

Drug action

Antipyretic and anti-inflammatory drug. The active ingredient - nimesulide, reduces the production of prostaglandins - substances responsible for the development of the inflammatory process and the focus. The effect of the drug Nise develops two hours after administration. Excreted by the kidneys, does not accumulate in the body.

In the form of a gel, it is used as an anesthetic, eliminating pain in the joints, both in a calm state and during movement. Neutralizes the morning stiffness of the joints and swelling.

Indications for use

It is used in osteoarthritis, osteoarthritis, rheumatism, bursitis, myalgia, and tendinitis. It is used as an analgesic after injuries, to eliminate pain in the spine, as well as for febrile syndrome and infectious pathologies.

The gel is used in inflammatory pathologies and degenerative disorders of the musculoskeletal system, in arthritis of the psoriatic and rheumatoid type, radiculitis, sciatica, lumbago, sprain.

Side effects

The body can respond to the reception of Nayz such undesirable reactions: headaches, abdominal pain, vomiting, heartburn, weakness, dizziness, nausea, perforation of the gastric mucosa, purpura, oliguria.

All these reactions are observed more often with the treatment with the Nise tablets, but if you use the gel, the probability of generalized side effects is practically excluded. When treating with an ointment, local side effects are possible: itching, urticaria, changes in pigmentation at the site of application. If the gel is applied to large areas of the skin, general adverse reactions may occur.

Cost and analogues

The cost of the drug Nise - from 250 rubles per pack, depending on the number of tablets. In this regard, we consider the cheaper analogues of Nise:

  • Nimesulide - from 90 to 196 rubles per pack,
  • Aponil - from 114 to 254 rubles per pack,
  • Nimika - from 229 to 584 rubles per pack,

Before choosing an analogue, consult with your doctor so as not to aggravate the condition with an incorrectly chosen drug.

Anti-inflammatory analogue Nise tablets in a more affordable price range.

Composition and release form

Available in tablets of 0.1 g each, in a package of 30, 20 and 10 pieces, in the form of a gel of 30 g per package, suspension for oral administration - 60 ml each, and also in the form of a powder for the preparation of a suspension of 0.1 g per bag, retail or thirty bags in the package.

In the composition of the drug nimesulide acts as an active substance. Auxiliary substances include lactose, cellulose, aerosil, talc, magnesium stearate. In the form of a gel auxiliary substance carbomer, macrogol, alcohol, propylene glycol.

Arthritis, arthrosis, osteoarthrosis. It is used for myalgia, arthralgia, bursitis, fever. The action of the suspension develops within half an hour, because it is used in acute sudden painful attacks.


Nise is contraindicated in ulceration of the gastric or intestinal wall, insufficiency of hepatic function, diabetes, aspirin triad and heart failure.

Banned for pregnant and lactating women, as well as under the age of twelve.

Side effects

The body can respond to the reception of Nayz such undesirable reactions: headaches, abdominal pain, vomiting, heartburn, weakness, dizziness, nausea, perforation of the gastric mucosa, purpura, oliguria.

All these reactions are observed more often with the treatment with the Nise tablets, but if you use the gel, the probability of generalized side effects is practically excluded. When treating with an ointment, local side effects are possible: itching, urticaria, changes in pigmentation at the site of application. If the gel is applied to large areas of the skin, general adverse reactions may occur.

Cost and analogues

The cost of the drug Nise - from 250 rubles per pack, depending on the number of tablets. In this regard, we consider the cheaper analogues of Nise:

  • Nimesulide - from 90 to 196 rubles per pack,
  • Aponil - from 114 to 254 rubles per pack,
  • Nimika - from 229 to 584 rubles per pack,

Before choosing an analogue, consult with your doctor so as not to aggravate the condition with an incorrectly chosen drug.

Anti-inflammatory analogue Nise tablets in a more affordable price range.

Composition and release form

Available in tablets of 0.1 g each, in a package of 30, 20 and 10 pieces, in the form of a gel of 30 g per package, suspension for oral administration - 60 ml each, and also in the form of a powder for the preparation of a suspension of 0.1 g per bag, retail or thirty bags in the package.

In the composition of the drug nimesulide acts as an active substance. Auxiliary substances include lactose, cellulose, aerosil, talc, magnesium stearate.In the form of a gel auxiliary substance carbomer, macrogol, alcohol, propylene glycol.

Arthritis, arthrosis, osteoarthrosis. It is used for myalgia, arthralgia, bursitis, fever. The action of the suspension develops within half an hour, because it is used in acute sudden painful attacks.


Strongly contraindicated in pregnancy, in childhood, with existing ulcerative diseases or hemorrhages, with aspirin asthma, liver failure or kidney failure.

With caution used with myocardial insufficiency, high blood pressure, as well as an allergic reaction to other anti-inflammatory drugs in history.

Side effects

The development of adverse reactions were rarely reported. Among those marked weakness, drowsiness, heartburn, nausea, urticaria. An allergic reaction can manifest anaphylactic shock. The quality characteristics of the blood may change, anemia, thrombocytopenia, and a decrease in blood density may occur.

The use of the gel may be accompanied by a rash, itchy or scaly redness, discoloration of the skin at the site of application.

Finding any undesirable effects, you should consult a doctor and stop using the drug.

Another Nise analogue with anti-inflammatory and analgesic activity.

Unwanted effects

In the treatment of Aponil, there may be abdominal pain, discomfort, the appearance of ulcers in the stomach and intestines, problems with the chair, vomiting. In rare cases, gastritis, cholestasis, flatulence, and hepatitis develop. Insomnia, dizziness and headaches, nightmarish dreams may occur.

The cardiovascular system may respond with leukopenia, tachycardia, high blood pressure, anemia, and blood clots. Among allergic reactions, toxic skin necrolysis, dermatitis, erythema, urticaria were noted. Other adverse effects: reduced concentration of vision, swelling, bronchospasm, edema, fever.

Anti-inflammatory drug, acting similar to Naizu, is used for pain syndromes accompanying diseases of the back and joints.

Drug description

Nise - NSAIDs. Selective inhibitor of COX-2 - an enzyme involved in the synthesis of prostaglandins - mediators of edema, inflammation and pain. The drug has anti-inflammatory, analgesic and antipyretic effects.

Reversibly inhibits the formation of prostaglandin E2, both in the focus of inflammation and in the ascending pathways of the nociceptive system, including the pathways of pain impulses in the spinal cord.

Reduces the concentration of short-lived prostaglandin N2from which prostaglandin E is formed by the action of prostaglandin isomerase2. Reducing the concentration of prostaglandin E2 leads to a decrease in the degree of activation of prostanoid receptors of the EP type, which is expressed in analgesic and anti-inflammatory effects.

To a small extent acts on COX-1, practically does not prevent the formation of prostaglandin E2 from arachidonic acid under physiological conditions, thereby reducing the number of side effects of the drug.

The drug inhibits platelet aggregation by inhibiting the synthesis of endoperoxides and thromboxane A2inhibits the synthesis of platelet aggregation factor. Suppresses the release of histamine, and also reduces the degree of bronchospasm caused by exposure to histamine and acetaldehyde.

The drug also inhibits the release of tumor necrosis factor alpha, causing the formation of cytokines.

It is shown that nimesulide is able to inhibit the synthesis of interleukin-6 and urokinase, thereby preventing the destruction of cartilage tissue. Inhibits the synthesis of metalloproteases (elastase, collagenase), preventing the destruction of proteoglycans and cartilage collagen.

It has antioxidant properties, inhibits the formation of toxic oxygen decomposition products by reducing the activity of myeloperoxidase. It interacts with glucocorticoid receptors, activating them by phosphorylation, which also enhances the anti-inflammatory effect of the drug.

When applied topically causes a weakening or disappearance of pain at the site of application of the gel, incl. pain in the joints at rest and when moving, reduces morning stiffness and swelling of the joints. Promotes increased range of motion.

Analogs of Russian production

Consider close substitutes for gel nesting among preparations from a domestic manufacturer. The table offers you to compare prices and descriptions of similar drugs.

The cheapest drug produced in Russia. Nonsteroidal anti-inflammatory drug in the form of tablets.

It has an analgesic effect. The tool is also produced in Macedonia.

The drug is available in granules for the preparation of suspensions. The composition of the drug includes nimesulide, as an active ingredient.

The solution is taken internally in order to reduce the heat, stop the inflammatory process, for pain relief.

The drug treats rheumatoid, headache, toothache, arthritis, myalgia. The tool is also produced in Romania.

Form release - tablets, gel, ointment, suspension, lozenges.

Medicines treat rheumatic diseases, relieve pain syndrome of various origins. The tool is also manufactured in India.

Ukrainian substitutes

Cheap analogs of the drug Nise gel of Ukrainian production have a different active ingredient, but similar indications for use. A list of modern medications is presented below.

  • Nobi gel. The tool will allow you to solve the problem than to replace nize gel. Effectively relieves pain, eliminates swelling, swelling. Indications for use - pain after injuries or bruises, tendovaginitis. The average price is 120–145 rubles.
  • Fort gel. Inexpensive analogue of the gel with the active ingredient ketoprofenom. It is applied topically to eliminate post-traumatic pain, with sprains, bruises. Sold as a gel in a tube of 30 and 50 g. The average price is 55–70 rubles.

Belarusian generics

Belarusian generics are an excellent option for replacement with a cheap drug with nimesulide.

The tool is available in the form of tablets, gel, powder.

The composition of the drug contains nimesulide, which is an analgesic, antipyretic and antimicrobial compound.

The drug reduces pain in gynecological and rheumatic diseases in the postoperative period.

Tablets, gel or suspension with nimesubel. Analogue of the price with cheaper price from the Belarusian manufacturer.

It is used in osteoarthritis, dysmenorrhea, and acute pain.

Non-steroidal anti-inflammatory agent in tablets to eliminate acute pain.

It has a number of contraindications described in the instructions. Banned during pregnancy and breastfeeding.

A means with the active substance nimesulide. Analgesic, antipyretic drug from a similar pharmacological group.

It is used for headache, dental, postoperative pain, as well as diseases of the musculoskeletal system.

Best Belarusian substitute for finding tablets.

Other foreign analogues

Modern imported synonyms will help you choose an inexpensive analogue of nayz in tablets and other dosage forms.

  • Aponil. The drug is produced in tablets. It is used to treat pain, reduce temperature, in inflammatory processes of the musculoskeletal system. Country of origin - Cyprus. The average price is 110–130 rubles.
  • Nimesil. The best import analog of nayz with similar action. The basis of the drug is nimesulide. Form release - powder for the preparation of the drink, which is consumed inside. The drug is produced in Italy, Germany. The average price is 25–690 rubles.
  • Nimulid. Nonsteroidal anti-inflammatory agent with antipyretic and analgesic function. Available in the form of tablets, gel, suspension. Country of origin - India. The average price is 130–355 rubles.
  • Nimika. Instant tablets. Indications for use - osteoarthritis, diseases of rheumatic origin, postoperative pain. Feverish conditions, dysmenorrhea. The drug is made in India. The average price is 120-250 rubles.

Such an approach in the choice of an anesthetic drug is unacceptable, due to the presence of a wide range of contraindications. Children, patients with heart failure, kidney disease, diabetes and hypertension should be monitored by a doctor for a possible reaction to the drug.

Cheap pills analogs nise

Remove moderate pain syndrome, the heat can be removed with ordinary paracetamol, Ibuprofen, which is referred to as the cheap analogues of Nise. Drugs are available without a prescription. Approved for use almost from childhood. Do not irritate the mucous membranes of the stomach and intestines, have a small percentage of side effects.

With the same active substance is an Indian drug Nimid Forte. For 10 pieces of tablets will have to pay only 55 rubles.

You can replace nise with Diclofenac. The cost of one package in the amount of 20 pieces is only 13.50 rubles. domestic production and 34.50 rubles. Serbian.

Gel analogue

Instead of Nise, you can use Diclofenac Gel. A tube with a capacity of 30 g costs about 60 rubles. Gel for external use manufactured in India with the same capacity - Nimid, can be bought for 65.44 rubles.

Analogues of Nays in the form of a gel are:

  • Fastum gel,

  • Diklak,
  • Artrum,
  • Nurofen,
  • Piroxicam,
  • Finalgel,
  • Voltarenes.

Analogs Nise in the form of ointment

You can use the ointment Diclofenac. A tube with a capacity of 30 g costs about 28.00 rubles. Similarly, Butadion ointment works. The cost of a tube is 86 rubles.

Drug Nise is recommended to be used after consultation with the doctor. Self-administration can cause side effects. You can not take medicine for problems with the digestive tract, internal bleeding, with renal, hepatic failure. At the same time, the drug is suitable for symptomatic treatment. Quickly eliminate bronchospasm, toothache, headache, menstrual. Take one tablet three times a day. The daily dose should not exceed 400 mg. The gel can cause an allergic reaction. If redness, burning of the skin, other unpleasant symptoms, treatment should be discontinued.

Nise with menstrual pain should be used when pain syndrome is strongly pronounced. In other cases, it is better to use analginum, ibuprofen. If Nise is prescribed by a doctor, the question of replacement should be discussed with him.

Nimesulide and its scope

In any form of release of the original drug Nise includes the active substance nimesulide. Clinical studies have shown its high efficacy not only as an anti-inflammatory and analgesic nonsteroidal agent. This is an effective way to resolve problems with joints, inter-articular cartilage tissues, tendons, their bruises, injuries and inflammatory processes. The effects and side effects of the original medication have been investigated in a clinical setting. This made it possible to supply it with protective documents and a patent, but at the same time it increased its value.

To date, Nise is available in tablets, gel and suspension, and this has expanded the scope of its application. Nise tablets (50 or 100 mg each), with a pronounced analgesic effect, are available in blister packs of 10 pieces each. Nise gel is a local drug applied to the affected areas. Suspension is given to children aged 2 years. The active ingredient in the composition of the drug is used for:

  • osteochondrosis,
  • gout
  • joint inflammations
  • rheumatism of different etiology,
  • arthritis
  • sciatica
  • radiculitis
  • injuries, bruises and damage to articular segments.

The gel allows you to use the therapeutic effect of nimesulide in those cases when it is necessary to minimize the side effects, and the dislocation of the pathology has this.

The need to replace the drug occurs when the financial situation of the patient does not allow the purchase of expensive drugs, or the individual intolerance of any component that is part of the original drug is detected. It’s easy to find an Nise analog, the main thing is to pick it up professionally so that the replacement is complete. Analogs gel Nise no worse than the original.

Types of analogues

When choosing tablets cheaper, certain subtleties should be taken into account, which may not be in the distributed lists. They may not even be in the instructions for use that guide pharmacists. There are 2 types of similar medicines:

Their fundamental difference lies in the active substance used. Genesis Nisa - a drug that uses nimesulide. In this case, the difference lies only in the availability of permits and cost. This is an inexpensive analogue of the Nise pills. Cheap medicines are not supplied with a patent, but are identical in the nimesulide that is included in them.

Complete analogues include drugs that have a similar effect, but the active substance in them is different. Nise has certain contraindications that the attending physician must take into account. Another medicine may have additional or fundamentally different side effects, which only a specialist can take into account. This also applies to:

  • impact on the ability to work with the mechanisms and driving vehicles,
  • interactions with other drugs
  • pharmacokinetics and characteristics of absorption and elimination from the body,
  • possible allergic reactions to the components added to a particular drug.

Russian counterparts in this respect are preferable both in terms of cost and the content of additives in a particular preparation. In addition, the presence of professionally written instructions in Russian will help to understand the nuances of prescription and dosage.

The misconception that a cheap drug is less effective than an expensive one is wrong in the case of nimesulide-containing generics, but consulting a specialist on dosage and intake features does not hurt. The analogue of the Russian production is no worse than the foreign original.

Positive and negative points

The undeniable advantages of replacing the use of more democratic nimisulide-containing generics is the difference in cost, sometimes significantly saving the patient's money. The mode of action and the technology of drugs practically do not differ from expensive analogues. A person with a low level of income can afford the treatment prescribed by the active substance.

The negative aspects include the lack of qualifications that are given to generics abroad, and sometimes the insufficient quality of the cleaning components included in the drug. This is due to the fact that brand-name drugs are manufactured by large pharmaceutical companies with new and technological equipment, and commercial counterparts produce small enterprises whose production equipment may be outdated or simply lower class.

When buying a drug with the same active substance, the probability of inconsistency is minimal. But in the acquisition of the drug, which is not a steroid anti-inflammatory, and is based on another active ingredient, you can make a mistake with the choice and not get the desired result. Ointment is easier to pick up because they are applied topically. You should be more careful with the pills, as they are ingested, interact with vital organs (GIT, kidneys, urinary system).

Medicines containing nimesulide

Nimesulide is considered to be the main and most common generic of Naiza. It is called the active substance contained in it, is in a wide retail sale and compares favorably with value. The list of drugs that can be replaced by Nise is quite wide, while some substitutes are not found in any pharmacy. Therefore, the list of analogues is given in abbreviated form:

  • Aktasulid (NSAID sulphonanilide class),
  • Ameolin (for the treatment of acute pain in primary dysmenorrhea and osteoarthritis),
  • Aponil (with similar Ameolin testimony),
  • Arthron (Complex, Triactiv, Flex, Hondrex - as recommended by the doctor depending on the nature of the pathology),
  • Mesulide,
  • Nymezik, Nimesil, Nimesulide, Nimulid, Nimefast, Novolid (all names are derived from the name Nimesulide, these drugs are full-fledged analogues of Naiz),
  • Structum (in osteoarthrosis and osteochondrosis),
  • Sulidin (a wide range of purposes for articular pathologies),
  • Flolide
  • Chondra-strength (including the warming ointment Chondra-strength, and Hondra-strength ointment).

The price of these drugs is an order of magnitude lower, but one medicine should be replaced with another, even if similar, with extreme caution. After all, it is no coincidence that the indications for use differ even in some analogues. Nimecil is produced in Italy, Nimesulide - in Romania and Macedonia, Nimulid - in India. Some of them are soluble in water and act faster, but the price of domestic drugs is less, and therefore they are preferable.

What should be remembered when choosing an analogue

Any medicine can turn into poison and have a negative effect if the wrong dosage is chosen, the drug is chosen incorrectly, poor-quality counterfeit products made in semi-homemade conditions are purchased. The patient should in no case independently carry out the replacement of tablets or ointment.

This requires the opinion of a specialist.If there is no time or opportunity to see a doctor, you should at least consult with a pharmacist or carefully study the abstract, which is always attached to the medication.

Neither very high nor extremely low cost is a fundamental indicator. You need to be guided only by the opinion of a specialist, who proceeds from considerations of expediency of application and his professional experience. Self-treatment rarely leads to positive results and can often have a negative effect on the condition of the body. Proper replacement of an expensive drug with a generic drug or a complete equivalent is the key to successful treatment with less material costs.